Many Oprah fans sent in comments thanking Oprah for her enthusiasm, informative shows and generosity. Besides wishing her the best of luck, viewers praised Oprah for getting them difficult times.

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Jazzyjane on Monday wrote: “Not before your show Oprah had I found any TV show that expanded my mind, brought me to tears (happy and sad), how to buy a bra!, eat healthy, lose weight (still trying) and take time for myself. I will miss you and your entire staff who made the show's my DO NOT DISTURB it's 4:00 p.m. 'me time.'"

Another viewer, Majormom, wrote: “When I joined the service I had her by my side. When I went on an assignment without my family, she kept me company on the lonely days and nights for over one year. And most importantly when I was medically retired from the military I prayed with Oprah that everything would be alright for me and my kids.”

You can send ABC7 your thank you messages, your farewells, and your fondest Oprah memories by leaving a comment on this page. Every day this week, we'll pick out our favorites and feature them here on WJLA.com