BOSTON (AP) - A 6-year-old Massachusetts girl whose love for Justin Bieber encouraged physicians and nurses at a Boston hospital to organize a pretend wedding to the pop star as she battled a rare brain cancer has died.

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The family of Avalanna Routh - who called herself Mrs. Bieber - said on their Twitter account that she died Wednesday morning. "Oh Avalanna, the brightest star - you took our hearts with you, our greatest Love," the family wrote.

During the pretend wedding, Avalanna held a yellow, green and purple bouquet of flowers, wore a T-shirt that said "Future Mrs. Bieber" and stood next to his portrait under a banner that declared them "Just Married." That sparked a social media campaign to help her meet the singer.

Bieber later arranged for the girl to meet him in New York, where they spent a couple of hours together before he tweeted that the experience was inspiring and the best thing he's ever done.